Human Alu Insertion Polymorphisms in North African Populations
نویسندگان
چکیده
منابع مشابه
Human Alu insertion polymorphisms in North African populations.
Several features make Alu insertions a powerful tool used in population genetic studies: the polymorphic nature of many Alu insertions, the stability of an Alu insertion event and, furthermore, the ancestral state of an Alu insertion is known to be the absence of the Alu element at a particular locus and the presence of an Alu insertion at the site that forward mutational change. This study ana...
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An analysis of eight Alu insertion loci (ACE, ApoA1, PV92, TPA25, NBC27, NBC102, NBC148 and NBC182) was carried out in three ethnic groups of the South Caucasus (Abkhazians, Armenians and Georgians). Genetic differentiation between these groups (Gst = 1%) was half as much as in European populations and four time less than in populations of Dagestan. Although it was not possible to determine a c...
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The inference of an individual's geographic ancestry or origin can be critical in narrowing the field of potential suspects in a criminal investigation. Most current technologies rely on single nucleotide polymorphism (SNP) genotypes to accomplish this task. However, SNPs can introduce homoplasy into an analysis since they can be identical-by-state. We introduce the use of insertion polymorphis...
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Alu insertion polymorphisms are widely distributed in the human genome. They are readily analysed and provide an interesting set of markers for human population genetic and forensic studies. The aim of this article is to present preliminary results from our ongoing project on a survey of Alu insertion polymorphisms in various human populations. INTRODUCTION Repetitive DNA sequences comprise a s...
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Genomic database mining has been a very useful aid in the identification and retrieval of recently integrated Alu elements from the human genome. We analyzed Alu elements retrieved from the GenBank database and identified two new Alu subfamilies, Alu Yb9 and Alu Yc2, and further characterized Yc1 subfamily members. Some members of each of the three subfamilies have inserted in the human genome ...
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ژورنال
عنوان ژورنال: Human Biology
سال: 2011
ISSN: 0018-7143,1534-6617
DOI: 10.3378/027.083.0503